Advocate Flea, Heartworm and Worm Treatment for Dogs Over 25kg is a spot-on flea and worm treatment for dogs weighing Over 25kg. Advocate Flea, Heartworm and Worm Treatment for Dogs Over 25kg is made from a special formula designed to treat and prevent gastrointestinal worms and protect against deadly heartworm. Advocate Flea, Heartworm and Worm Treatment for Dogs Over 25kg is also effective in breaking the flea life-cycle and stops fleas from feeding within 3 to 5 minutes of application and kills adult fleas and larvae within 20 minutes. Advocate Flea, Heartworm and Worm Treatment for Dogs 10-25kg is applied monthly to provide month long flea and worm protection and it is also water resistant. Advocate Flea, Heartworm and Worm Treatment for DogsOver 25kgcomes in a pack of 1.